PTBP2

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PTBP2
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PTBP2, PTBLP, brPTB, nPTB, polypyrimidine tract binding protein 2
External IDs MGI: 1860489 HomoloGene: 23162 GeneCards: PTBP2
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_019550
NM_001310711

RefSeq (protein)

NP_001297640.1
NP_062423.1
NP_001297640
NP_062423

Location (UCSC) Chr 1: 96.72 – 96.82 Mb Chr 3: 119.72 – 119.78 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Polypyrimidine tract binding protein 2, also known as PTBP2, is a protein which in humans is encoded by the PTBP2 gene.[3][4]

Function[edit]

The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract-binding protein PTBP1 but it is expressed primarily in the brain.[4]

References[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.