P wave (electrocardiography)
Absence of the P wave with a flat baseline may indicate:
A P wave with decreased amplitude can indicate hyperkalemia.
The P wave is a summation wave generated by the depolarization front as it transits the atria. Normally the right atrium depolarizes slightly earlier than left atrium since the depolarization wave originates in the sinoatrial node, in the high right atrium and then travels to and through the left atrium. The depolarization front is carried through the atria along semi-specialized conduction pathways including Bachmann's bundle resulting in uniform shaped waves. Depolarization originating elsewhere in the atria (atrial ectopics) result in P waves with a different morphology from normal. If at least three different shaped P waves can be seen in a given ECG lead tracing, this implies that even if one of them arises from the SA node, at least two others are arising elsewhere. This is taken as evidence of multiple (i.e. at least two) ectopic foci, and is called multifocal (or more correctly, multiform) atrial rhythm if the rate is ≤100) or multifocal atrial tachycardia if the rate is over 100. This appears particularly commonly in exacerbations of chronic obstructive lung disease. Notched and bi-phasic P waves are commonly seen in the ECG. Some of the morphological forms of P wave are:
Bifid P waves (known as P mitrale) indicate left-atrial abnormality - e.g. dilatation  or hypertrophy. If the baseline has totally an irregular form this suggests fibrillatory waves of atrial fibrillation or possibly artefact; a saw tooth shaped baseline suggests the flutter waves of atrial flutter. NB with either of these rhythms, if the ventricular rate is fast, the fibrillatory or flutter waves can easily be misinterpreted as P waves.
If P waves are not clearly delineated in the surface ECG, a Lewis lead may be used to better visualize P waves.
This occurs a mean of 320 ms after the end of the P-wave, with a duration of 2-3 times that of the P-wave and a polarity always opposite to that of the P wave. It is represented on the surface ECG by a so-called Ta wave. The clinical relevance of this is that, although a normal phenomenon, the nadir of the Ta wave can occur just after the QRS complex and cause ST depression similar to (and easily mistaken with) that occurring with disease states such as cardiac ischaemia.
- Longmore, Murray (2004). Oxford Handbook of Clinical Medicine 8th edition page 90. Oxford University Press. ISBN 0-19-852558-3.
- Reeves WC, Hallahan W, Schwiter EJ, Ciotola, TJ, Buonocore E, Davidson W (1981). "Two-dimensional echocardiographic assessment of electrocardiographic criteria for right atrial enlargement.". Circulation 64: 387–391. doi:10.1161/01.CIR.64.2.387. PMID 6454512.
- Kastor JA (1990). "Multifocal Atrial Tachycardia". N Engl J Med 322 (24): 1713–1717. doi:10.1056/NEJM199006143222405. PMID 2188131.
- Kothari SA, Apiyasawat S, Asad N, Spodick DH (2006). "Evidence supporting a new rate threshold for multifocal atrial tachycardia". Clin Cardiol 28 (12): 3561–3563. doi:10.1002/clc.4960281205. PMID 16405199.
- ECG learning at University of Utah
- Munuswamy K, Alpert MA, Martin RH, Whiting RB, Mechlin NJ (1983). "Sensitivity and specificity of commonly used electrocardiographic criteria for left atrial enlargement determined by m-mode echocardiography". Am J of Cardiol 53 (6): 829–832. doi:10.1016/0002-9149(84)90413-2. PMID 6230922.
- Smith, SW. "Atrial Repolarization Wave Mimicking ST Depression". Retrieved 22 October 2014.