Pancreatic polypeptide receptor 1

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Neuropeptide Y receptor Y4
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols NPY4R ; NPY4-R; PP1; PPYR1; Y4
External IDs OMIM601790 MGI105374 HomoloGene116086 IUPHAR: 307 ChEMBL: 4877 GeneCards: NPY4R Gene
RNA expression pattern
PBB GE PPYR1 210956 at tn.png
More reference expression data
Species Human Mouse
Entrez 5540 19065
Ensembl ENSG00000204174 ENSMUSG00000048337
UniProt P50391 Q61041
RefSeq (mRNA) NM_001278794 NM_008919
RefSeq (protein) NP_001265723 NP_032945
Location (UCSC) Chr 10:
46.46 – 46.47 Mb
Chr 14:
34.14 – 34.15 Mb
PubMed search [1] [2]

Pancreatic polypeptide receptor 1, also known as Neuropeptide Y receptor type 4, is a protein that in humans is encoded by the PPYR1 gene.[1][2]

Selective Ligands[edit]



See also[edit]


  1. ^ Lutz CM, Richards JE, Scott KL, Sinha S, Yang-Feng TL, Frankel WN, Thompson DA (Feb 1998). "Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not clustered with receptors specific for neuropeptide Y and peptide YY". Genomics 46 (2): 287–90. doi:10.1006/geno.1997.5024. PMID 9417917. 
  2. ^ "Entrez Gene: PPYR1 pancreatic polypeptide receptor 1". 
  3. ^ Ziemek R, Schneider E, Kraus A, Cabrele C, Beck-Sickinger AG, Bernhardt G, Buschauer A (2007). "Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence". Journal of Receptor and Signal Transduction Research 27 (4): 217–33. doi:10.1080/10799890701505206. PMID 17885919. 

External links[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.