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Virus classification
Group: Group I (dsDNA)
Order: Megavirales
Family: Pandoraviridae
Genus: Pandoravirus

Pandoraviridae is a family of double-stranded DNA viruses that infect amoebae. There is only one genus in this family: Pandoravirus. Within this genus, two species have been described to date: Pandoravirus dulcis and Pandoravirus salinus.[1][2]


The viruses were discovered in 2013.[1][2]


The viruses in this family are the second largest known virus (~1 micrometer) in capsid length, after Pithovirus (1.5 micrometer).[3] Pandoravirus has the largest viral genome known, containing double-stranded DNA of 1.9 to 2.5 megabase pairs.[4][1]


These viruses appear to be related to the phycodnaviruses.[5]


  1. ^ a b c Yong, Ed (18 July 2013). "Giant viruses open Pandora's box". Nature. doi:10.1038/nature.2013.13410. 
  2. ^ a b Nadège Philippe; Matthieu Legendre; Gabriel Doutre; et al. (July 2013). "Pandoraviruses: Amoeba Viruses with Genomes Up to 2.5 Mb Reaching That of Parasitic Eukaryotes". Science. 341 (6143): 281–6. Bibcode:2013Sci...341..281P. doi:10.1126/science.1239181. PMID 23869018. 
  3. ^ Sirucek, Stefan (3 March 2014). "Ancient "Giant Virus" Revived From Siberian Permafrost". National Geographic. 
  4. ^ Brumfiel, Geoff (18 July 2013). "World's Biggest Virus May Have Ancient Roots". National Public Radio. Retrieved 18 July 2013. 
  5. ^ Yutin N, Koonin EV (2013). "Pandoraviruses are highly derived phycodnaviruses". Biol. Direct. 8: 25. doi:10.1186/1745-6150-8-25. PMC 3924356Freely accessible. PMID 24148757.