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Pankrác is a neighborhood of Prague, Czech Republic. It is located south of the city centre on the hills of the right bank of the Vltava River and is part of the Prague 4 quarter situated in the district of Nusle. The name derives from the local baroque initially very old church of St Pancras (Pankrác in Czech), which is filial to the parish church of St. Wenceslas in Nusle.
Since the 1970s, several high-rise commercial buildings have been built in Pankrác, and still others are being discussed amid some criticism that the skyline may threaten the historical character of Prague.