Pantothenoylcysteine decarboxylase

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pantothenoylcysteine decarboxylase
Identifiers
EC number4.1.1.30
CAS number9024-65-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a pantothenoylcysteine decarboxylase (EC 4.1.1.30) is an enzyme that catalyzes the chemical reaction

N-[(R)-pantothenoyl]-L-cysteine pantetheine + CO2

Hence, this enzyme has one substrate, N-((R)-pantothenoyl)-L-cysteine, and two products, pantetheine and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase (pantetheine-forming). Other names in common use include pantothenylcysteine decarboxylase, and N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase. This enzyme participates in pantothenate and coa biosynthesis.

References[edit]

  • Brown GM (June 1957). "Pantothenylcysteine, a precursor of pantetheine in Lactobacillus helveticus". The Journal of Biological Chemistry. 226 (2): 651–61. PMID 13438850.