Paramethasone

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Paramethasone
Paramethasone.svg
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Identifiers
Synonyms (6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
ECHA InfoCard 100.000.155
Chemical and physical data
Formula C22H29FO5
Molar mass 392.461 g/mol
3D model (Jmol)
 NYesY (what is this?)  (verify)

Paramethasone is a fluorinated glucocorticoid with anti-inflammatory and immunosuppressant properties.[1]

References[edit]

  1. ^ Toxnet: Paramethasone

Further reading[edit]

  • Wershil, B. K.; Furuta, G. T.; Lavigne, J. A.; Choudhury, A. R.; Wang, Z. S.; Galli, S. J. (1995). "Dexamethasone and cyclosporin a suppress mast cell-leukocyte cytokine cascades by multiple mechanisms". International Archives of Allergy and Immunology. 107 (1–3): 323–4. doi:10.1159/000237015. PMID 7613160. 
  • Riccardi, C; Cifone, M. G.; Migliorati, G (1999). "Glucocorticoid hormone-induced modulation of gene expression and regulation of T-cell death: Role of GITR and GILZ, two dexamethasone-induced genes". Cell death and differentiation. 6 (12): 1182–9. doi:10.1038/sj.cdd.4400609. PMID 10637434. 
  • Lavista Llanos, S; Roldán, A (1999). "Effect of dexamethasone on nitric oxide (NO.) production by cultured astrocytes". Biocell. 23 (1): 29–35. PMID 10904533.