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Paraoxon

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This is an old revision of this page, as edited by DePiep (talk | contribs) at 19:51, 2 April 2016 (Remove redundant parameters InChI, InChIKey (StdInChI, StdInChIKey are used). See Talk (via AWB script)). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Paraoxon
Clinical data
ATC code
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • diethyl 4-nitrophenyl phosphate
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.005.657 Edit this at Wikidata
Chemical and physical data
FormulaC10H14NO6P
Molar mass275.195 g/mol g·mol−1
3D model (JSmol)
  • [O-][N+](=O)c1ccc(OP(=O)(OCC)OCC)cc1
  • InChI=1S/C10H14NO6P/c1-3-15-18(14,16-4-2)17-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3 checkY
  • Key:WYMSBXTXOHUIGT-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Paraoxon is a parasympathomimetic which acts as an acetylcholinesterase inhibitor. It is an organophosphate oxon, and the active metabolite of the insecticide parathion. It is also used as an ophthalmological drug against glaucoma. Paraoxon is one of the most potent acetylcholinesterase-inhibiting insecticides available, around 70% as potent as the nerve agent sarin, and so is now rarely used as an insecticide due to the risk of poisoning to humans and other animals. It is easily absorbed through skin, and was used as an assassination weapon by the apartheid-era South African chemical weapons program Project Coast.[1]

References

  1. ^ NTI Country Overviews:South Africa:Chemical Capabilities:Paraoxon
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