Parathion S

From Wikipedia, the free encyclopedia
Parathion S
Parathion S.svg
Names
Preferred IUPAC name
O,O-Diethyl S-(4-nitrophenyl) phosphorothioate
Other names
S-Phenyl parathion
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C10H14NO5PS/c1-3-15-17(14,16-4-2)18-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3
    Key: DSVCXDBXXBVSEB-UHFFFAOYSA-N
  • CCOP(=O)(OCC)Sc1ccc(cc1)[N+](=O)[O-]
Properties
C10H14NO5PS
Molar mass 291.26 g·mol−1
Appearance Pale yellow crystalline solid
Hazards
Lethal dose or concentration (LD, LC):
107 μg/kg (mice, intraperitoneal)[1]
4.41 mg/kg (rats, oral)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Parathion S is an organophosphate related to the organophosphate insecticide paraoxon and parathion. It's the structural isomer of parathion. Parathion S is a potent acetylcholinesterase inhibitor.[2][3]

See also[edit]

References[edit]

  1. ^ a b "ChemIDplus".
  2. ^ DIGGLE, WM; GAGE, JC (September 1951). "Cholinesterase inhibition in vitro by OO-diethyl O-p-nitrophenyl thiophosphate (parathion, E 605)". The Biochemical Journal. 49 (4): 491–4. doi:10.1042/bj0490491. PMC 1197537. PMID 14886312.
  3. ^ ALDRIDGE, WN; DAVISON, AN (December 1952). "The inhibition of erythrocyte cholinesterase by tri-esters of phosphoric acid. II. Diethyl p-nitrophenyl thionphosphate (E605) and analogues". The Biochemical Journal. 52 (4): 663–71. doi:10.1042/bj0520663. PMC 1198077. PMID 13018298.