|Finless sole, Pardachirus marmoratus|
Pardachirus marmoratus, also known as the finless sole or the Red Sea Moses sole, is a small fish from the Red Sea that secretes an ichthyotoxic milky substance from the base of its dorsal and anal fins. This secretion contains pardaxin, a lipophillic peptide that causes severe plasma membrane disruption resulting in cell leakage. The pardaxin containing secretion is used as a defensive mechanism against predators including sharks. Pardaxin is irritating to predator fish, particularly affecting the sensitive gills. Dr. Eugenie Clark conducted much of the early work on Pardachirus marmoratus.
There is much biotechnological interest in pardaxin, early interest focused on potential shark repellent applications while newer research foucuses on antimicrobial and neurotoxic potential of pardaxin and its analogues.
|This article needs additional citations for verification. (March 2017) (Learn how and when to remove this template message)|
- Clark, Eugenie; Gorge, Anita (June 1979). "Toxic soles, Pardachirus marmoratus from the Red Sea and P. pavoninus from Japan, with notes on other species". Environmental Biology of Fishes. 4 (2): 103–123. doi:10.1007/bf00005447. Retrieved 15 Feb 2016.
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