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Pathrusim were descendants of Mizraim (i.e., Egypt) according to the genealogies in Genesis, who inhabited Pathros (i.e., Upper Egypt).

In Parry, J. H. (ed.). "10:23". Book of Jasher. Translated by Moses, Samuel. , the Pathrusim and Casluhim intermarried resulting in the Pelishtim, Azathim, Gerarim, Githim, and Ekronim.