Patrick Soon-Shiong

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Patrick Soon-Shiong
Native name Soon-Shiong黄馨祥
Born July 29, 1952 (1952-07-29) (age 63)
Port Elizabeth, South Africa
Nationality American
Alma mater University of Witwatersrand
University of British Columbia
University of California at Los Angeles Medicine & Surgery
Occupation Surgeon, medical researcher at UCLA, businessman and philanthropist
Net worth Increase US$12.5 billion (July 2015)[1]
Spouse(s) Michele B. Chan

Patrick Soon-Shiong (Chinese: 陈颂雄.Soon-Shiong黄馨祥; pinyin: Huáng Xīnxiáng, Mandarin pronunciation: [xu̯ɑ̌ŋ ɕín ɕi̯ɑ̌ŋ]; born July 29, 1952) is a South African-born American surgeon, medical researcher, businessman, philanthropist, and professor at University of California at Los Angeles. He is currently chairman of the Chan Soon-Shiong Family Foundation and chairman and CEO of the Chan Soon-Shiong Institute for Advanced Health, National LambdaRail, the Healthcare Transformation Institute and NantWorks, LLC.[2] He is minority owner of the Los Angeles Lakers and is ranked by Forbes as the wealthiest American in the healthcare industry and the wealthiest man in Los Angeles with a net worth of US$12.3 billion.[3]

Early life[edit]

Soon-Shiong was born in Port Elizabeth, South Africa to Chinese immigrant parents who fled from China during World War II.[4] His parents are from Taishan in Guangdong, China.[4]


He graduated from high school at age 16 and graduated 4th out of 189 in his class when received his MBBCh medical degree at age 23 from the University of Witwatersrand, where he studied on a scholarship.[5] Soon-Shiong completed his medical internship at Johannesburg’s General Hospital. He then studied at the University of British Columbia, where he earned a MSc degree and received research awards from the American College of Surgeons, the Royal College of Physicians and Surgeons of Canada, and the American Association of Academic Surgery, making him the first resident of the university to do so.[6] He initiated his surgical training at University of California, Los Angeles (UCLA), after moving to the United States, becoming a board-certified surgeon. Dr Soon-Shiong is a Fellow of the Royal College of Surgeons (Canada) and a Fellow of the American College of Surgeons.[6][7]


Soon-Shiong performed the world's first full pancreas transplant in 1987.[7]

Soon-Shiong developed an experimental treatment for Type-1 diabetes known as encapsulated human islet transplant. He performed the world's first encapsulated human-to-human and pig-to-human islet transplants in 1993.

He invented the nation’s first FDA approved protein nanoparticle delivery technology for the treatment of metastatic breast cancer, doubling the response rate in patients. He received support from the National Institutes of Health, and the NASA Space Shuttle program. The drug Abraxane is now approved in over 40 countries, and currently in trials for lung, melanoma, gastric, and pancreatic cancer. Soon-Shiong is a co-holder of over 114 issued patents and has over 440 patent applications to date worldwide, he has also published more than 100 scientific papers. He has developed and sold two multi-billion dollar pharmaceutical companies, American Pharma Partners (APP) and Abraxis BioScience (ABII). APP was responsible for the only safe supply of Heparin in the United States in 2008, when supplies from other sources were found to be tainted.[8]

Soon-Shiong was on the faculty of UCLA Medical School from 1983 to 1991 and an associate investigator at the Center for Ulcer Research and Education from 1984 to 1987.[9] He left UCLA in 1991 to start a diabetes and cancer biotechnology firm that eventually became American Pharmaceutical Partners and Abraxis BioScience. Soon-Shiong founded American Pharmaceutical Partners (APP) in 1997. He sold the company to Fresenius SE for $5.6 billion[10] in July 2008. Soon-Shiong sold Abraxis BioScience, maker of his drug Abraxane to Celgene in 2010 in cash-and-stock deal, valued at over $3 billion.[11] He returned to UCLA during 2009 as a professor of microbiology, immunology, molecular genetics, and bioengineering.

Current work[edit]

Soon-Shiong founded a new company, NantWorks, in September 2011. The company has stated that its mission is "to converge ultra-low power semiconductor technology, supercomputing, high performance, secure advanced networks and augmented intelligence to transform how we work, play, and live."[12] [13] Soon-Shiong first founded NantHealth in 2007 to provide fiber-optic, cloud-based data infrastructure to share healthcare information.[14] In October, 2012, Soon-Shiong announced that NantHealth’s supercomputer-based system and network is able to analyze the genetic data from a tumor sample in 47 seconds and transfer the data in 18 seconds. The goal of developing this infrastructure and digital technologies is to share the genomic information among sequencing centers, medical research hubs and hospitals, and to advance cancer research and big science endeavors such as The Cancer Genome Atlas.[15] On January 2013, he founded another biotech company, NantOmics, to develop cancer drugs based on kinase inhibitors. Together with the sister company NantHealth, the two companies are part of the umbrella organization, NantWorks. Soon-Shiong stated that NantWorks’s vision of the future cancer treatment is a convergence of multiple technologies that include diagnostics, supercomputing, network model of sharing data on tumor genes and personalized concoction of cancer drugs combination for multi-targeted attacks. The goal is to manage the cancer and achieve a sustained disease-free state.[16]

In 2010, with Arizona State University and the University of Arizona, Soon-Shiong founded the Healthcare Transformation Institute (HTI), which he dubs a "do-tank".[17] HTI's mission is to promote a paradigm shift in health care in the United States by better integrating the three now separate domains of medical science, health delivery, and healthcare finance.[2][18]

Soon-Shiong heads the CSS Institute for Advanced Health, founded in 2011 with a mission to provide high-speed computing capabilities for human genotyping to target specific cancer treatments, as well as technologies for the better management of chronic disease. Through the CSS Institute, Soon-Shiong is working to create a national health information network for the secure sharing of biomedical information. He is supporting the development of various wireless technologies for the better management of chronic disease.[19]

Soon-Shiong is on several boards. These include the Board of Directors of the Mendez National Institute of Transplantation,[20] and the board of directors for the Technology Council for the Center for Cancer Nanotechnology Excellence at Northwestern University.[21] He leads other organizations concurrently. He is Chairman of the National Coalition for Health Integration,[22] and is the Executive Director of the UCLA Wireless Health Institute.[23]

In 2010, in partnership with the LA Business Journal, Soon-Shiong founded the “Patrick Soon-Shiong Innovation Awards”; the first winners of these annual awards were six companies from the media, entertainment, engineering and aerospace sectors.[24] The third annual Patrick Soon-Shiong Innovation Awards will take place in the fall of 2012.

In October 2010, he acquired a 4.5% stake in the Los Angeles Lakers after buying the shares of Earvin "Magic" Johnson. [11][25]

In July 2015, Soon-Shiong initiated an IPO for NantKwest (formerly ConkWest) that represented the highest value biotech IPO in history, at a market value of $2.6 billion. [26]

In 2015 Forbes estimated his fortune at $12.2 billion, ranking him #37 among US billionaires, the wealthiest American in the healthcare industry, and the wealthiest person in Los Angeles.


Soon-Shiong and his wife, Michele B. Chan, fund several health-related projects through the Chan Soon-Shiong Family Foundation. In 2007 they pledged US $1billion to support healthcare transformation and a national health information highway. The Foundation has given a total of $135 million to the Saint John's Health Center in Santa Monica, California.

It gave a guarantee of $100 million that enabled the replacement of closed Martin Luther King Jr./Drew Medical Center with the new Martin Luther King, Jr. Community Hospital in Willowbrook. Its Summer 2015 opening restored healthcare access to the largely underserved residents of South Los Angeles.[27]

In 2010, Soon-Shiong and Chan were asked to and did join Bill Gates and Warren Buffett in taking The Giving Pledge, by which some of the wealthiest Americans have pledged to give the majority of their wealth to charitable causes. They will donate half their wealth.[28][29]

In 2011 Soon-Shiong and Chan endowed a new Chair at the USC Viterbi School of Engineering, to support research at intersection of engineering and medicine, specifically computer science, mobile vision, and robotics.[30]


Soon-Shiong’s research has been recognized by national and international awards such as the Association for Academic Surgery Award for Research, the American College of Surgeons Schering Scholar, the Royal College Physicians and Surgeons Research Award, the Peter Kiewit Distinguished Membership in Medicine Award, and the International J.W. Hyatt Award for Service to Mankind. Soon-Shiong received the 2006 Gilda Club Award for the advancement of cancer medicine and is a recipient of a 2007 Ellis Island Medal of Honor as well as the St. Mary Medical Center Life Achievement Award in 2007 and the St. John’s Health Center Caritas Award in 2007. In 2008, he received the Medical Visionary Award from the Pancreatic Cancer Action Network for his work in pancreatic cancer & the Los Angeles County Economic Development Council (LAEDC) Eddy Award in November 2009. The Los Angeles Business Journal recognized him as their 2010 Business Person of the Year, and the National Library of Medicine awarded Soon-Shiong the Distinguished Medical Science Award. The University of Arizona awarded him an honorary doctorate in December 2010, and Visiting Professor of the Imperial College of London in 2011.[31]


  1. ^ Forbes: Patrick Soon-Shiong July 29, 2015
  2. ^ a b "Billionaire Patrick Soon-Shiong Wants To Remake The U.S. Health Care System". 10 October 2010. Retrieved 9 February 2012. 
  3. ^ "Patrick Soon-Shiong - Forbes". 6 July 2015. Retrieved July 6, 2015. 
  4. ^ a b "Biotech Kahuna Patrick Soon-Shiong". GoldSea. Retrieved 22 October 2012. 
  5. ^ Armstrong, David (10 June 2003). "Vindication". Forbes. Retrieved 3 April 2015. 
  6. ^ a b "Patrick Soon-Shiong: Putting the patient first". University of the Witwatersrand. October 2009. Retrieved 3 April 2015. 
  7. ^ a b "Patrick Soon-Shiong, M.D.". UCLA Engineering. UCLA. Archived from the original on 3 April 2015. Retrieved 3 April 2015. 
  8. ^ "AAFSAA Celebrates Dr. Patrick Soon-Shiong Recipient of Honorary Doctor of Science from the UA". 18 December 2010. Retrieved 9 February 2012. 
  9. ^
  10. ^ Cullen, Angela (7 July 2008). "Fresenius Kabi Buys APP to Enter U.S. Generics Market". Bloomberg L.P. Retrieved 20 October 2010. 
  11. ^ a b Crowe, Deborah (18 October 2010). "Celgene Closes Abraxis Acquisition". Los Angeles Business Journal. Retrieved 20 October 2010. 
  12. ^ Shawn Baldwin (September 20, 2014). "Dr. Patrick Soon Shiong Generates Billions of Value Creation in Medicine". Fast Company. 
  13. ^ Dolan, Brian (Sep 8, 2011). "'Soon-Shiong’s big rollup gets a name: NantWorks'". Retrieved 24 January 2012. 
  14. ^ "Company Overview of NantHealth, LLC". Bloomberg Businessweek. 27 February 2013. Retrieved 27 February 2013. 
  15. ^ McBride, Ryan (4 October 2012). "Biotech billionaire’s supercomputer cuts cancer analysis to 47 seconds". Retrieved 27 February 2013. 
  16. ^ Tirrell, Meg (28 January 2013). "Cancer Researcher-Turned-Billionaire Starts New Company". Retrieved 26 February 2013. 
  17. ^ Soon-Shiong, Patrick (Sep 8, 2011). "'Message from the CEO and President'". Retrieved 9 April 2012. 
  18. ^ Soon-Shiong, Pattrick (Sep 5, 2012). "'Patrick Soon-Shiong Talks With ASU's Michal Crow about the Imminent, Hoped-For Healthcare Revolution'". 
  19. ^ "Phoenix Mayor Phil Gordon to Join Chan Soon-Shiong Institute for Advanced Health". 16 November 2011. Retrieved 9 February 2012. 
  20. ^ "Board of Directors". Mendez National Institute of Transplantation. Retrieved 20 October 2010. 
  21. ^ "Northwestern University Center for Cancer Nanotechnology Excellence". Northwestern University. Retrieved 9 April 2012. 
  22. ^ "The National Coalition for Health Integration" (PDF). p. 2. Retrieved 20 October 2010. 
  23. ^ "UCLA names Soon-Shiong executive director of Wireless Health Institute". UCLA Newsroom. Retrieved 20 October 2010. 
  24. ^ "Soon-Shiong, Innovator" (PDF). 29 November 2010. Retrieved 9 February 2012. 
  25. ^ "'Earvin "Magic" Johnson Sells Share of Lakers to Dr. Patrick Soon-Shiong'". Oct 18, 2010. Retrieved 9 February 2012. 
  26. ^ "NantKwest Gives Biotech Another Big IPO". Retrieved 29 July 2015. 
  27. ^ 'Pharmaceutical executive donates $100 million to St. John's Health Center' in "Los Angeles Times", October 2, 2009 [1]
  28. ^ "The Giving Pledge". Retrieved May 30, 2012. 
  29. ^ Vincent Li (2010-09-29). "Patrick Soon-Shiong Chan Pledges to Donate Half His Wealth". China Times. Retrieved May 30, 2012. 
  30. ^ Soon-Shiong Gives Multi-Million Dollar Gift to USC Engineering School', in Beverly Hills Courier, September 29, 2011 [2]
  31. ^ 'Visionary healthcare entrepreneur and philanthropist, Dr. Patrick Soon-Shiong, to speak at UCLA Engineering commencement' in "UCLA Engineering", 2011 [3]