As a bandleader, he recorded under the name Paul Humphrey and the Cool Aid Chemists, with keyboardist Clarence MacDonald, guitarist David T. Walker, and bassist Bill Upchurch. In 1971, this ensemble had two hits, "Cool Aid" (US #29, US Black Singles #14) and "Funky L.A." (US Black Singles #45). He also recorded an album as head of the Paul Humphrey Sextet in 1981.
He also recorded with Steely Dan, Frank Zappa, Jerry Garcia, Jimmy Smith, The Four Tops, Al Kooper, Jackie DeShannon, Natalie Cole, Albert King, Quincy Jones, Dusty Springfield, Jean-Luc Ponty, Michael Franks, Maria Muldaur, Marc Bolan and others.
Humphrey also was the featured drummer for both the Lawrence Welk orchestra and television show from 1976 to 1982. He and his wife Joan are the parents of two children, Pier and Damien, who appeared with their father on the Welk show's annual Christmas episode.
- Paul Humphrey and the Cool Aid Chemists (Lizard Records, 1969) US #170, US Black Albums #31
- Detroit b/w Cool Aid (Lizard Records, 1969) 45 rpm, 2:31
- Supermellow (Blue Thumb, 1973)
- America, Wake Up (Blue Thumb Records, 1973)
- Paul Humphrey Sextet (Discovery Records, 1981)
With Monty Alexander
- Alexander the Great (Pacific Jazz, 1964)
With Mel Brown
With Kenny Burrell
- 'Round Midnight (Fantasy, 1972)
With Jerry Garcia
- Pure Jerry: Keystone Berkeley, September 1, 1974 (Jerry Made, 2004)
- Welcome Home (World Pacific, 1968)
With Stan Kenton
- Hair (Capitol, 1969)
With Charles Kynard
- Reelin' with the Feelin' (Prestige, 1969)
- Woga (Mainstream, 1972)
- Your Mama Don't Dance (Mainstream, 1973)
With Les McCann
- The Gospel Truth (Pacific Jazz, 1963)
- Soul Hits (Pacific Jazz, 1963)
- Spanish Onions (Pacific Jazz, 1964)
- McCanna (Pacific Jazz, 1964)
- A Bag of Gold (Pacific Jazz, 1963-64 )
- McCann/Wilson (Pacific Jazz, 1964) with the Gerald Wilson Orchestra
- But Not Really (Limelight, 1965)
- Beaux J. Pooboo (Limelight, 1965)
- Live at Shelly's Manne-Hole (Limelight, 1966)
- Live at Bohemian Caverns - Washington, DC (Limelight, 1967)
- Another Beginning (Atlantic, 1974)
With Gerald Wilson
- Ron Wynn (1935-10-10). "Paul Humphrey | Biography". AllMusic. Retrieved 2014-05-28.
- Paul Humphrey & the Cool Aid Chemists Billboard Singles, Allmusic.com
- Paul Humphrey Billboard Singles, Allmusic.com
- "Let's Get It On - Marvin Gaye | Credits". AllMusic. Retrieved 2014-05-28.
- "The Drummers of Steely Dan". Granatino.com. 1998-08-25. Retrieved 2014-05-28.
- "paul humphrey". United-mutations.com. 1935-10-10. Retrieved 2014-05-28.
- Billboard, Allmusic.com
- "Paul Humphrey and His Cool Aid Chemists – Detroit". Flea Market Funk. 2008-02-13. Retrieved 2014-05-28.