After completing his medical studies at Leipzig (in 1901) he completed his army service, then joined Dr Ludolf von Krehl in Tübingen as an assistant physician. Krehl inspired Morawitz in his studies of blood-related pathology. In 1907 he completed a disseration on blood circulation (for his Habilitation), and he was appointed in the same year as chief clinician of the University clinic at Freiburg im Breisgau. He progressed to become the Ordinarius and Director of the Medical inpatients at Greifswald in 1913, and in 1921 he took up a position in Würzburg. Finally, in 1926, he assumed the chair of Medicine in Leipzig. He died aged 57 of a heart attack.
Morawitz was a pioneer in the study of coagulation, and a 1905 landmark paper is still regarded as a springboard for further study of the physiology of blood; he perfected observations made earlier by Alexander Schmidt and described four coagulation factors: fibrinogen (I), prothrombin (II), thrombokinase (III) and calcium (IV). He also pioneered blood transfusion, initially without the benefit of blood typing, and studied angina and the use of quinidine as an antiarrhythmic. He established a blood bank in Leipzig.
- Boulton F (February 2006). "A hundred years of cascading - started by Paul Morawitz (1879-1936), a pioneer of haemostasis and of transfusion". Transfus Med. 16 (1): 1–10. doi:10.1111/j.1365-3148.2006.00643.x. PMID 16480434.
- Morawitz P (1905). "Die Chemie der Blutgerinnung". Ergebn Physiol (in German). 4: 307–422. doi:10.1007/BF02321003.
- Deutsche Gesellschaft für Kardiologie. "Paul-Morawitz-Preis" (in German). Retrieved 2010-11-11.