Pegylated interferon

From Wikipedia, the free encyclopedia
Jump to: navigation, search

Pegylated interferon (PEG-INF) is a class of medication that includes three different drugs as of 2012:[1]

In these formulations, Polyethylene glycol (PEG) is added to make interferon last longer in the body.[3] They are used to treat both hepatitis B,[4] hepatitis C[1] and multiple sclerosis.[2]

Pegylated interferon is contraindicated in patients with hyperbilirubinaemia.


  1. ^ a b editor, Emilio Jirillo, (2008). Hepatitis C virus disease : immunobiology and clinical applications ([Online-Ausg.] ed.). New York: Springer. p. 237. ISBN 978-0-387-71375-5. 
  2. ^ a b Kieseier BC, Calabresi PA.; Calabresi (2012). "PEGylation of Interferon-β-1a: A Promising Strategy in Multiple Sclerosis". CNS Drugs. 26 (3): 205–14. doi:10.2165/11596970-000000000-00000. PMID 22201341. 
  3. ^ Hepatology Focus: Update on Hepatitis C Treatment: Pegylated Interferon
  4. ^ Clinical Hepatology. [S.l.]: Springer Berlin Heidelberg. 2010. p. 765. ISBN 978-3-642-04509-7.  |first1= missing |last1= in Authors list (help)