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Pemtumomab (trade name Theragyn) is a mouse monoclonal antibody used to treat cancer. The substance has affinity to various types of cancer, like ovarian cancer and peritoneal cancer, via the polymorphic epithelial mucin (PEM or MUC-1) and delivers the radioisotope Yttrium-90 into the tumour. As of 2009[update], it is undergoing Phase III clinical trials.
- Oei, AL; Moreno, M; Verheijen, RH; Sweep, FC; Thomas, CM; Massuger, LF; Von Mensdorff-Pouilly, S (2008). "Induction of IgG antibodies to MUC1 and survival in patients with epithelial ovarian cancer". International Journal of Cancer. Journal International Du Cancer. 123 (8): 1848–53. PMID 18661524. doi:10.1002/ijc.23725.
- Antisoma's Lead Product, Pemtumomab Granted European Orphan Drug Status
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