Penemue is a watcher in Book of Enoch lore. He is a curer of stupidity in man, mentioned in Bereshith Rabba. As an angel associated with Abraxiel (Abraxas), Penemue (whose name means "the inside") was also likely of the order of healing angels called the Labbim.
The name of the fourth is Penemue: he discovered to the children of men bitterness and sweetness;
And pointed out to them every secret of their wisdom.
He taught men to understand writing, and the use of ink and paper.
Therefore numerous have been those who have gone astray from every period of the world, even to this day.
For men were not born for this, thus with pen and with ink to confirm their faith;
Since they were not created, except that, like the angels, they might remain righteous and pure.
Nor would death, which destroys everything, have effected [sic] them;
But by this their knowledge they perish, and by this also its power consumes them.
- Davidson, Gustav (1967), A Dictionary of Angels, Including The Fallen Angels, Entry: Penemue, p. 222, Library of Congress Catalog Card Number: 66-19757
- Enoch 1 68:9-16
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