Pennsauken Creek drains 33 square miles (85 km2) of southwestern Burlington County and northern Camden County and joins the Delaware River near Palmyra.
The North Branch of the Pennsauken is in Burlington County, while the South Branch forms the boundary between Burlington and Camden counties. The tide affects the 3.8-mile (6.1 km) main stem and the first few miles up the branches. Both the North and South branches are approximately 10 miles long.
The Pennsauken Creek faces problems from agricultural and urban runoff, as well as wastewater treatment facilities. Landfills are also a source of contamination for the Pennsauken Creek, as well as industrial pollution near the mouth of the river's main stem. 
The name of the creek, "Pennsauken," most likely came from "Pemisoakin," an Indian village in the area. 
North Branch Pennsauken Creek
South Branch Pennsauken Creek
- U.S. Geological Survey. National Hydrography Dataset high-resolution flowline data. The National Map, accessed April 1, 2011
- Initial Surface Water Quality Characterization and Assessment Report (Based on DEP Data) for Watershed Management Area 19 (Rancocas, Pennsauken, Cooper, Pompeston and Mill Creek Watersheds), New Jersey Department of Environmental Protection, February 1, 1999
- Pennsauken Creek Watershed
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