From Wikipedia, the free encyclopedia
The compounds currently available for clinical use are:
- sodium stibogluconate (Pentostam; manufactured by GlaxoSmithKline; available in United States [through the Centers for Disease Control only] and UK), which is administered by slow intravenous injection.
- meglumine antimoniate (Glucantim; manufactured by Aventis; available in Brazil, France and Italy), which is administered by intramuscular or intravenous injection.
The pentavalent antimonials can only be given by injection: there are no oral preparations available.
- Lima EB, Porto C, Motta JCO, Sampaio RNR.Treatment of American cutaneous leishmaniasis. An Bras Dermatol. 2007;82(2):111-24.
- Olliaro P, Guerin P, Gerstl S (2005). "Treatment options for visceral leishmaniasis: a systematic review of clinical studies done in India, 1980–2004". Lancet Infect Dis 5 (12): 763–774. doi:10.1016/S1473-3099(05)70296-6. PMID 16310148.
|This antiinfective drug article is a stub. You can help Wikipedia by expanding it.|