Pentolinium

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Pentolinium
Pentolinium.png
Systematic (IUPAC) name
1-methyl-1-[5-(1-methylpyrrolidin-1-ium-1-yl)pentyl]pyrrolidin-1-ium
Identifiers
CAS Registry Number 144-44-5
52-62-0 (tartrate salt)
PubChem CID: 5850
DrugBank DB01090
ChemSpider 5641
UNII ULL76WPU5X
ChEMBL CHEMBL1271
Chemical data
Formula C15H32N2
Molecular mass 240.43 g/mol

Pentolinium is a ganglionic blocking agent which acts as a nicotinic acetylcholine receptor antagonist. It can be used as an antihypertensive drug during surgery or to control hypertensive crises. It works by binding to the acetylcholine receptor of adrenergic nerves and thereby inhibiting the release of noradrenaline and adrenaline. Blocking this receptor leads to smooth muscle relaxation and vasodilatation. Pentolinium can be given orally, injected intramuscularly or administered intravenously.[citation needed]

Overview[edit]

It's molecular formula is C15H32N2+2.[1]

References[edit]

External links[edit]