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Peptic is an adjective that refers to any part of the body that normally has an acidic lumen, or is related to or promotes digestion.[1] 'Peptic' is medical and veterinary terminology, most often used in the context of humans.[2]

Peptic anatomy[edit]

The peptic areas of the human body under normal circumstances are the stomach and duodenum. A person with gastroesophageal reflux disease(it may be caused by failure of cardiac or gastroesophageal sphincter or if cardiac sphincter remains relaxed) may have an acidic esophagus, particularly at the inferior (lower) end. Also, a person with a Meckel's diverticulum may have cells that produce acid within the diverticulum and therefore may be prone to peptic ulcers and perforation.[2]

A person with an unusual anatomy, such as one who has had a gastrectomy or an esophagectomy with transplantation of the ileum to replace the esophagus, may experience acidity in parts of the body that would not normally be acidic.

In all normal humans and in almost all humans, only the gastrointestinal tract is peptic.[2]

Peptic diseases[edit]

A common problem with the peptic areas of the body is peptic ulcer. These ulcers are most commonly caused by bacteria, and not by the acidic environment.[2]


  1. ^ "Definition of PEPTIC".
  2. ^ a b c d Parkman, Henry P.; Fisher, Robert Stephen (2006). The Clinician's Guide to Acid/peptic Disorders and Motility Disorders of the Gastrointestinal Tract. SLACK Incorporated. ISBN 978-1-55642-716-9.