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Structural formula of perfluorobutane
Ball-and-stick model of perfluorobutane
Preferred IUPAC name
Other names
Perfluorobutane (no longer recommended[1])
Perflubutane (USAN)
Halocarbon 610
355-25-9 YesY
3D model (Jmol) Interactive image
ChemSpider 13862701 N
ECHA InfoCard 100.005.983
EC Number 206-580-3
KEGG D05440 YesY
PubChem 9638
Molar mass 238.03 g·mol−1
Density 11.21 kg/m3 (gas, 101.3 kPa at boiling point)[2]
1594 kg/m3 (liquid, 101.3 kPa at boiling point)[2]
Melting point −128 °C (−198 °F; 145 K)[3]
Boiling point −1.7 °C (28.9 °F; 271.4 K)[2]
1.5 mg/L (101.3 kPa)[3]
log P > 3.93 (n-octanol/water)[3]
Vapor pressure 330.3 kPa (at 25 °C)[3]
Viscosity 0.0001218 Poise[2]
Safety data sheet MSDS at Linde Gas
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Perfluorobutane (PFB) is a colorless gas. It is a simple fluorocarbon with a n-butane skeleton and all the hydrogen atoms replaced with fluorine atoms. It is used as a replacement for Halon 1301 fire extinguishers,[4] as well as the gas component for newer generation microbubble ultrasound contrast agents. Sonazoid[5] is one such microbubble formulation developed by Amersham Health that uses perfluorobutane for the gas core.


  1. ^ Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 33. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4. The prefix ‘per-’ is no longer recommended. 
  2. ^ a b c d "Perfluorobutane (R610)". Gas Encyclopaedia. Air Liquide. Retrieved November 1, 2012. 
  3. ^ a b c d "Summary Report: PERFLUOROBUTANE". 
  4. ^ "Perfluorobutane — Full Public Report" (PDF). National Industrial Chemicals Notification and Assessment Scheme. 1996. 
  5. ^ "Sonoazoid - US TIP".