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Pestilence may refer to:
- Infectious disease
- Pestilence, one of the four Horsemen of the Apocalypse symbolizing Plague (contagious disease) in some interpretations of the book of Revelation
- Pestilence (band), a Dutch death metal group
- Pestilence (comics), a Marvel Comics supervillain, based on the biblical horseman
- "The Pestilence", a song by Kreator from Pleasure to Kill
- Pestilence wort, a perennial plant native to Europe and northern Asia.
- Prelude to Pestilence, a scenario in the Realmz fantasy adventure and role-playing video game
disambiguation page lists articles associated with the title Pestilence.
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