Pethelinos (Greek: Πεθελινός) is a small village in the Serres regional unit of Central Macedonia, Greece 22 km away from the town of Serres, and 2.5 km from the Strymon River. The village has 474 inhabitants (2011). It is part of the municipal unit Emmanouil Pappas municipality. The village has one church of Saint Nikolaos close to the village's square and one chapel of Prophet Elias, built on a hill just outside the village.
The region of Pethelinos was inhabited since prehistoric times. Near the village has been discovered the site of an ancient lakeside settlement, which survived throughout antiquity and probably bore the name "Potolinos".In Byzantine times the village is mentioned in documents as "Potholinos".
- "Απογραφή Πληθυσμού - Κατοικιών 2011. ΜΟΝΙΜΟΣ Πληθυσμός" (in Greek). Hellenic Statistical Authority.
- D. C. Samsaris, Recherches sur l' histoire de la navigation des habitants du cours inférieur du Strymon dans l' Antiquité, Thracia Pontica I (Sozopol 1979), p. 261
-  Dimitrios C. Samsaris, A History of Serres (in the Ancient and Roman Times) (in Greek), Thessaloniki 1999, p. 81-82 (Website of Municipality of Serres)
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