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Systematic (IUPAC) name
Legal status
Legal status
CAS Number 129-83-9 N
ATC code none
PubChem CID 8523
ChemSpider 16735960 YesY
UNII 0600L2M6EZ YesY
Chemical data
Formula C17H26N2O
Molar mass 274.40 g/mol
 NYesY (what is this?)  (verify)

Phenampromide is an opioid analgesic from the ampromide family of drugs, related to other drugs such as propiram and diampromide. It was invented in the 1960s[1] by American Cyanamid Co.[2] Although never given a general release, it was trialled and 50mg codeine ≈ 60mg phenampromide. Tests on the 2 isomers showed that all of the analgesic effects were caused by the (S) isomer.

Phenampromide produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.

Phenampromide is in Schedule I of the Controlled Substances Act 1970 of the United States as a Narcotic with ACSCN 9638 with a zero aggregate manufacturing quota as of 2014. The free base conversion ratio for salts includes 0.88 for the hydrochloride.[3] It is listed under the Single Convention for the Control of Narcotic Substances 1961 and is controlled in most countries in the same fashion as is morphine.


  1. ^ Portoghese PS. Stereochemical Studies on Medicinal Agents II. Absolute Configuration of (-)-Phenampromide. Journal of Medicinal Chemistry. 1965 Mar;8:147-50.
  2. ^ US Patent 3016382
  3. ^