Phenylacetone

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Phenylacetone
Skeletal formula
Ball-and-stick model
Names
IUPAC name
1-Phenylpropan-2-one
Other names
Benzyl methyl ketone; Methyl benzyl ketone; Phenyl-2-propanone
Identifiers
103-79-7 YesY
ChEBI CHEBI:52052 YesY
ChemSpider 21106366 YesY
Jmol 3D model Interactive image
KEGG C15512 YesY
PubChem 7678
UNII O7IZH10V9Y YesY
Properties
C9H10O
Molar mass 134.18 g·mol−1
Appearance Colorless, pleasant odor
Density 1.006 g/mL
Melting point −15 °C (5 °F; 258 K)
Boiling point 214 to 216 °C (417 to 421 °F; 487 to 489 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Phenylacetone is an organic compound with the chemical formula C6H5CH2C(O)CH3. It is a colorless oil that is soluble in organic solvents. This substance is used in the manufacture of methamphetamine and amphetamine, where it is commonly known as P2P. Due to the illicit uses in clandestine chemistry, it was declared a schedule II controlled substance in the United States in 1980.[1] In humans, phenylacetone occurs as a metabolite of amphetamine via oxidative deamination.

Applications[edit]

Phenyl acetone is used as an intermediate in the production of pesticides and anticoagulants.[citation needed]

Amphetamine metabolism[edit]

Metabolic pathways of amphetamine in humans
Graphic of several routes of amphetamine metabolism
Phenylacetone
Para-
Hydroxylation
Para-
Hydroxylation
Para-
Hydroxylation
Beta-
Hydroxylation
Beta-
Hydroxylation
Oxidative
Deamination
Oxidation
Glycine
Conjugation

See also[edit]

References[edit]