Phenylmercuric nitrate

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Phenylmercuric nitrate
Phenylmercuric nitrate.svg
Phenylmercuric-nitrate-3D-vdW.png
Names
IUPAC name
nitrooxy(phenyl)mercury
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.000.221 Edit this at Wikidata
EC Number
  • 200-242-9
RTECS number
  • OW8400000
UNII
UN number 1895
  • InChI=1S/C6H5.Hg.NO3/c1-2-4-6-5-3-1;;2-1(3)4/h1-5H;;/q;+1;-1
    Key: PDTFCHSETJBPTR-UHFFFAOYSA-N
  • C1=CC=C(C=C1)[Hg]O[N+](=O)[O-]
Properties
C6H5HgNO3
Molar mass 339.702 g/mol
Melting point 176–186 °C (349–367 °F; 449–459 K)
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Toxic
GHS labelling:
GHS05: CorrosiveGHS06: ToxicGHS08: Health hazardGHS09: Environmental hazard
Danger
H301, H314, H372, H410
P260, P264, P270, P273, P280, P301+P310, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P314, P321, P330, P363, P391, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Phenylmercuric nitrate is an organomercury compound with powerful antiseptic and antifungal effects.[1] It was once commonly used as a topical solution for disinfecting wounds, but as with all organomercury compounds it is highly toxic, especially to the kidneys, and is no longer used in this application. However it is still used in low concentrations as a preservative in eye drops for ophthalmic use, making it one of the few organomercury derivatives remaining in current medical use.[2]

See also[edit]

References[edit]

  1. ^ Xu, Y.; He, Y.; Li, X.; Gao, C.; Zhou, L.; Sun, S.; Pang, G. (2013). "Antifungal effect of ophthalmic preservatives phenylmercuric nitrate and benzalkonium chloride on ocular pathogenic filamentous fungi". Diagnostic Microbiology and Infectious Disease. 75 (1): 64–7. doi:10.1016/j.diagmicrobio.2012.09.008. PMID 23102555.
  2. ^ Kaur, I. P.; Lal, S.; Rana, C.; Kakkar, S.; Singh, H. (2009). "Ocular preservatives: Associated risks and newer options". Cutaneous and Ocular Toxicology. 28 (3): 93–103. doi:10.1080/15569520902995834. PMID 19505226. S2CID 9806996.