Phenylpyrazole insecticides are a class of chemically-related broad-spectrum insecticides. The chemical structures of these insecticides are characterized by a central pyrazole ring with a phenyl group attached to one of the nitrogen atoms of the pyrazole.
Phenylpyrazole insecticides function by blocking glutamate-activated chloride channels in insects. Mammals do not have this type of chloride channel, making them much less susceptible to its effects. However, they do have the capacity to disrupt epithelial cells in the human intestine and adversely impact human health.
- Vidau, C.; Brunet, J. L.; Badiou, A.; Belzunces, L. P. (2009). "Phenylpyrazole insecticides induce cytotoxicity by altering mechanisms involved in cellular energy supply in the human epithelial cell model Caco-2". Toxicology in Vitro. 23 (4): 589–597. doi:10.1016/j.tiv.2009.01.017.
- "Compendium of Pesticide Common Names: Insecticides". alanwood.net.
- Media related to phenylpyrazole insecticides at Wikimedia Commons