Philip Randle

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Sir Philip John Randle (16 July 1926 – 26 September 2006) was a British medical researcher.[1][2][3]

The Randle cycle is named for him.

Early life and education[edit]

Born 16 July 1926 in Nuneaton, Warwickshire, Randle was educated at King Edward VI Grammar School, Nuneaton; Sidney Sussex College, Cambridge, where he read the Nature Sciences Tripos, graduating with first-class honours and an M.A.; University College Hospital and the UCL Medical School, where he read medicine and graduated with an M.D.[4]

After qualifying as a medical doctor, Randle returned to the University of Cambridge to undertake a Ph.D. under Professor Frank George Young.[5] For his doctoral thesis entitled "Studies on the Metabolic Action of Insulin", he was awarded his Ph.D. in 1955 and was immediately appointed Lecturer in Biochemistry at the University.[6]


Early career[edit]

Research and academic career[edit]

Randle was a prominent diabetes mellitus researcher who described the eponymous Randle cycle of carbohydrate and fat metabolism.[5]

Personal life[edit]

Randle was married to Elizabeth Harrison (d. 2004) and had son Peter and three daughters, Susan, Sally, and Rosalind.[5][6]


  1. ^ "Bristol University | News from the University | Professor Sir Philip Randle". Retrieved 2008-12-05. 
  2. ^ Denton RM, Ashcroft SJ (July 2007). "A tribute to the life and work of Philip Randle". Diabetologia. 50 (7): 1359–61. doi:10.1007/s00125-007-0677-1. PMID 17473914. 
  3. ^ Sugden MC (May 2007). "In appreciation of Sir Philip Randle: the glucose-fatty acid cycle". Br. J. Nutr. 97 (5): 809–13. doi:10.1017/S0007114507659054. PMID 17408519. 
  4. ^ P.J. Randle, D.A. Priestman, S. Mistry, A. Halsall. (1994.) Mechanisms modifying glucose oxidation in diabetes mellitus, Diabetologia, 37 (Suppl 2):S155-S161.
  5. ^ a b c H. Brown. (2006.) Sir Philip Randle, The Lancet, 368(9548):1644.
  6. ^ a b "Professor Sir Philip Randle - Obituaries". The Independent. 2 December 2006.