Philip Seeman

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Philip Seeman
Born (1934-02-08) February 8, 1934 (age 85)
Winnipeg, Manitoba
AwardsOrder of Canada

Philip Seeman, OC FRSC (born February 8, 1934) is a Canadian schizophrenia researcher and neuropharmacologist, known for his research on dopamine receptors.

Born in Winnipeg, Manitoba, Seeman was raised in Montreal. He received a Bachelor of Science degree, honours physics & physiology (1955), a Master of Science degree, physiology of transport & secretion (1956), and a Doctor of Medicine (1960) from McGill University. In 1966, he received a Ph.D. in life sciences from Rockefeller University.

In 1967, Seeman became an assistant professor in the Department of Pharmacology at the University of Toronto. In 1970, he was appointed a professor.

In 1974, having spent years in search for the binding site of antipsychotic medication, he discovered the dopamine D2 receptor, the basis for the dopamine hypothesis of schizophrenia.[1][2]

In 2001, he was made an Officer of the Order of Canada "for his research on dopamine receptors and their involvement in diseases such as schizophrenia, Parkinson's and Huntington's".[3]

In 1985, he was made a Fellow of the Royal Society of Canada.[4]

He is married to Dr. Mary V. Seeman.[5]


  1. ^ P. Seeman, M. Chau-Wong, J. Tedesco & K. Wong (November 1975). "Brain receptors for antipsychotic drugs and dopamine: direct binding assays". Proceedings of the National Academy of Sciences of the United States of America. 72 (11): 4376–4370. Bibcode:1975PNAS...72.4376S. doi:10.1073/pnas.72.11.4376. PMC 388724. PMID 1060115.CS1 maint: multiple names: authors list (link)
  2. ^ "People". CMAJ. 151 (8): 1186–1187. 1994. PMC 1337253.
  3. ^ Order of Canada citation
  4. ^
  5. ^ "Most Wikipedia profiles are about men – these women in Australia are hoping to change that". SBS News. Retrieved 27 July 2019.


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