This article needs additional citations for verification. (April 2018) (Learn how and when to remove this template message)
|Immunohistochemical staining of the lung of a seal with PDV infection|
|Encephalitis in the cerebral cortex of a harbor seal with PDV, stained with hematoxylin and eosin|
Phocine distemper virus
Phocine morbillivirus, formerly Phocine distemper virus (PDV), is a paramyxovirus of the genus Morbillivirus that is pathogenic for pinniped species, particularly seals. Clinical signs include laboured breathing, fever and nervous symptoms.
In 2002, an epidemic of PDV along the North Sea coast resulted in the deaths of 21,700 seals, estimated to be 51% of the population.
The suddenness of the emergence of PDV and related viruses in aquatic mammals has implicated environmental changes as the cause. Pollutants have been posited as contributors by interfering with the ability of animals to mount a defense against infection. Alternatively, climate change and overfishing may have forced aquatic species that naturally harbour the viruses into new areas, exposing immunologically susceptible populations.
- "ICTV Taxonomy history: Phocine morbillivirus" (html). International Committee on Taxonomy of Viruses (ICTV). Retrieved 15 January 2019.
- "Marine Mammals: Viral Diseases". The Merck Veterinary Manual. 2006. Retrieved 2007-06-18.
- Duignan, PJ; Van Bressem, MF; Baker, JD; Barbieri, M; Colegrove, KM; De Guise, S; de Swart, RL; Di Guardo, G; Dobson, A; Duprex, WP; Early, G; Fauquier, D; Goldstein, T; Goodman, SJ; Grenfell, B; Groch, KR; Gulland, F; Hall, A; Jensen, BA; Lamy, K; Matassa, K; Mazzariol, S; Morris, SE; Nielsen, O; Rotstein, D; Rowles, TK; Saliki, JT; Siebert, U; Waltzek, T; Wellehan, JF (22 December 2014). "Phocine distemper virus: current knowledge and future directions". Viruses. 6 (12): 5093–134. doi:10.3390/v6125093. PMC 4276944. PMID 25533658.