Molybdophosphoric acid; dodecamolybdophosphoric acid
3D model (JSmol)
|Molar mass||1825.25 g/mol|
|Density||1.62 g/ml (hydrate)|
|Melting point||79-90 °C|
|Main hazards||Oxidiser (hydrate)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
Phosphomolybdic acid, also known as dodeca molybdophosphoric acid or PMA, is a yellow-green chemical compound that is freely soluble in water and polar organic solvents such as ethanol. It is used as a stain in histology and in organic synthesis
Phosphomolybdic is used as a stain for developing thin-layer chromatography plates, staining phenolics, hydrocarbon waxes, alkaloids, and steroids. Conjugated unsaturated compounds reduce PMA to molybdenum blue. The color intensifies with increasing number of double bonds in the molecule being stained.
Phosphomolybdic acid is also occasionally used in acid-catalyzed reactions in organic synthesis. It has been shown to be a good catalyst for the Skraup reaction for the synthesis of substituted quinolines.
- "Phosphomolybdic acid hydrate - Safety data sheet" (PDF). www.sigmaaldrich.com. 2016-07-18. Retrieved 2018-10-06.
- "Masson's Trichrome for Muscle and Collagen". StainsFile.
- "Stains for Developing TLC Plates" (PDF). McMaster University.
- Burstein, Shlomo (1953). "Reduction of Phosphomolybdic Acid by Compounds Possessing Conjugated Double Bonds". Analytical Chemistry. 25 (3): 422–424. doi:10.1021/ac60075a012. ISSN 0003-2700 – via ACS Publications.
- Chaskar, Atul; Padalkar, Vikas; Phatangare, Kiran; Langi, Bhushan; Shah, Chetan (2010). "Miceller-Mediated Phosphomolybdic Acid: Highly Effective Reusable Catalyst for Synthesis of Quinoline and Its Derivatives". Synthetic Communications. 40 (15): 2336–2340. doi:10.1080/00397910903245141. ISSN 0039-7911 – via Taylor & Francis Online.