Phosphoramidate

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A phosphoramidate is a phosphate that has an NR2 instead of an OH group. The structure of phosphoramidic acid (phosphoramidate), (HO)2PONH2, is present in PubChem.[1]
A phosphorodiamidate is a phosphate that has two of its OH groups substituted by NR2 groups.

Examples[edit]

Two examples of natural phosphoramidates are phosphocreatine and the phosporamidate formed when histidine residues in histidine kinases are phosphorylated.[2] An example of a phosphorodiamidate is Morpholino which is used in molecular biology.


See also[edit]

References[edit]

  1. ^ "phosphoramidic acid - PubChem". Pubchem.ncbi.nlm.nih.gov. 2013-09-25. Retrieved 2014-01-14. 
  2. ^ "Two-Component Signal Transduction". Annual Review of Biochemistry. 2000-07-01. Retrieved 2015-06-07.