Phyllomedusa oreades is a species of frog in the Hylidae family, endemic to the Brazilian savanna. Its natural habitats are subtropical or tropical dry shrubland, subtropical or tropical dry lowland grassland, and rivers.
P. oreades skin secretions research has suggested therapeutic value, especially as an anti-T. cruzi agent to prevent infections during blood transfusion.
- Silvano, D. 2004. Phyllomedusa oreades. 2006 IUCN Red List of Threatened Species. Downloaded on 21 July 2007.
- "Dermaseptins from Phyllomedusa oreades and Phyllomedusa distincta Anti-Trypanosoma cruzi Activity without Cytotoxicity to Mammalian Cells" 
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