After spending his youth career at Fogape Yaoundé and the relatively eminent regional side Canon Yaoundé, Womé moved to Italy from Cameroon in the summer of 1996 to start his professional career. He began his senior career at Vicenza Calcio and spent almost seven years playing in Italy until moving to English Premier League side Fulham FC in August 2002. He was sold to Bologna F.C. 1909 in a co-ownership deal for 6 billion lire in 1999, until Roma acquired him for 2 billion lire in the same summer that Francesco Antonioli, Amedeo Mangone and Alessandro Rinaldi joined Roma for 10 billion lire, 13 billion lire and 6 billion lire respectively. In June 2000 Bologna acquired Womé outright for a fee of 1 million lire. During his time in England at Fulham, Womé scored once in the league, in a 3–0 win over West Brom in February 2003.
Womé was a regular starter in the left back position for Cameroon during the late 1990s and early 2000s. He was a key member of the squads that won consecutive African Cup of Nations titles in 2000 and 2002 and the Olympic gold medal in 2000. All three tournaments were won on penalty shoot-outs, and Womé was a taker in all three victories. In the Olympic gold medal match, Womé scored the fifth and decisive penalty to win the title for his country. He also scored from the spot in the 2000 African Cup of Nations final, but his penalty in the following tournament was saved by Senegal's Tony Sylva. Womé also played as Cameroon's first choice left back in the 1998 and 2002 World Cups.
During a press conference several days afterward, Womé said about the penalty: “No one wanted to take that penalty. No one. Neither Samuel Eto'o nor our captain Rigobert Song, because they knew what could have happened if they missed. I have always had the courage and I went to the spot.” He also claimed that some Cameroon fans wanted to kill him.