In 2006, Piet Hein Donner recorded a rap song together with Meester G to explain his point of view on the Dutch soft-drug policy. It was a reply to a song by Gerd Leers, Mayor of Maastricht, (with punk band Heideroosjes), which called for a more progressive policy which would not only regulate the selling of soft drugs, but also legalise their production.
On 13 September 2006, Donner was the subject of controversy when he suggested Islamic law could be established in the Netherlands by democratic means. He responded by a clarification that he was not advocating such a scenario but warning against it. That same month, a report of the investigative commission into a fire at Schiphol Airport jail was released, condemning Dutch government officials. Donner, as responsible justice minister, resigned in aftermath of the report's conclusions. His successor was Ernst Hirsch Ballin, who had been justice minister in the third Lubbers cabinet. Four months later, Donner was appointed Minister of Social Affairs and Employment in the new Cabinet, Balkenende IV.