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Chemical and physical data
Molar mass381.508 g/mol g·mol−1
3D model (JSmol)

Pipoxizine (INN) is a first-generation antihistamine as well as serotonin antagonist of the diphenylmethylpiperazine group related to hydroxyzine.[1][2] It was investigated as a bronchodilator but was never marketed.[1][3][4]


  1. ^ a b C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1619–. ISBN 978-0-412-46630-4.
  2. ^ World Health Organization (1988). International Nonproprietary Names (INN) for Pharmaceutical Substances. W.H.O.
  3. ^ Brunner A, Gartmann J, Studler H. "Pipoxizine, a New Bronchodilator". Lung. 154 (2): 143.
  4. ^ Neukirch F, Korobaeff M, Verdier F, Timsit G, Fay M, Drutel P (1978). "[Effect of a histamine aerosol in 20 subjects with histamine hyperreactivity. Application to a study of the protective properties of pipoxizine]". Rev Inst Hyg Mines (Hasselt) (in French). 33 (4): 191–5. PMID 45187.