Pirlimycin

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Pirlimycin
Structural formula
Space-filling model of pirlimycin molecule
Clinical data
Routes of
administration
Intramammary
ATCvet code QJ51FF90 (WHO)
Identifiers
CAS Number 79548-73-5 YesY
ChemSpider 138508 N
UNII LM19JT6G5K N
KEGG D08391 YesY
ChEMBL CHEMBL1652611 N
Chemical and physical data
Formula C17H31ClN2O5S
Molar mass 410.164 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Pirlimycin hydrochloride belongs to the lincosamide class of antimicrobials. Under the trade name Pirsue,[1] it is used in the treatment of mastitis in cattle.

Activity[edit]

Pirlimycin is active against Gram-positive bacteria, specifically Staphylococcus aureus and coagulase negative species of Staphylococcus and Streptococcus. It has no activity against Gram-negative bacteria.[2]

Mechanism of action[edit]

It is bacteriostatic and acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome.

References[edit]