In 1697 the Duchess married Gian Gastone de' Medici, who later became Grand Duke of Tuscany. They lived in the castle of Ploschkowitz. Anna Maria Franziska dominated her weak husband, which drove him into the arms of alcohol. He deplored her behaviour, "capriciousness, peevish faces and sharp words". Gian Gastone stayed with his wife for a mere ten months, before fleeing to Prague. The Tuscan grand duchess refused to come to Tuscany, despite her husband's constant protestations. She believed that the Medici were in the habit of murdering their consorts.