As a pianist, she has given performances around the world, including at the Sydney Opera House, and other venues in Europe and Japan. She also has had occasional honorary starring roles in Thai soap operas, dramas, and musicals, including Nemiraj - Scenes from Ten Lives of the Buddha. A socialite, she has been an occasional model for Thai fashion magazines and society publications.
Ploypailin married her long-time boyfriend David Wheeler in Hawaii, United States on 25 August 2009. They have two sons, Maximus Wheeler and Leonardo Wheeler.