|Systematic IUPAC name
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Polyglutamic acid (PGA) is a polymer of the amino acid glutamic acid (GA). Gamma PGA (Poly-γ-glutamic acid, γ-PGA) - the form where the peptide bonds are between the amino group of GA and the carboxyl group at the end of the GA side chain - is a major constituent of the Japanese food natto. Gamma PGA is formed by bacterial fermentation.
The other isomer, poly-α-glutamic acid is being used as a drug delivery system in cancer treatment and research is underway for its application in a treatment of type I diabetes and its potential use in the production of an AIDS vaccine.
Heavy metal removal
G-PGA covalently incorporated into microfiltration membranes via attachment to their membrane pore surfaces exhibited super-high heavy metal sorption ability.Ref:Bhattacharyya et al. (1998) G-PGA was found to bind and efficiently remove .99.8% of lead ions from water via a suitable low-pressure ultrafiltration technique.Ref:Inbaraj et al. (2006)