A post-viral cough is a lingering cough that follows a viral respiratory tract infection, such as a common cold or flu and lasting up to eight weeks. Post-viral cough is a clinically recognized condition represented within the European medical literature. Patients usually experience repeated episodes of post-viral cough. The heightened sensitivity in the respiratory tract is demonstrated by inhalation cough challenge.
One possible cause for post-viral cough is that the receptors that are responsible for stimulating the cough during the respiratory tract infection are up-regulated by respiratory tract infection and continue to stimulate even after the virus has disappeared.
Post-viral cough can be resistant to treatment. Post-viral cough usually goes away on its own; however, cough suppressants containing codeine may be prescribed. A study has claimed theobromine in dark chocolate is more effective. Inhaled steroids may work in some patients. Running or increased cardiovascular activity can help clear the respiratory tract. Often the cause is post-nasal drip, and so nasal steroids or pseudoephedrine might also be helpful.
- Kastelik JA, Aziz I, Ojoo JC, Thompson RH, Redington AE, Morice AH (February 2005). "Investigation and management of chronic cough using a probability-based algorithm". Eur. Respir. J. 25 (2): 235–43. doi:10.1183/09031936.05.00140803. PMID 15684286.
- Chung KF, Lalloo UG (October 1996). "Diagnosis and management of chronic persistent dry cough". Postgrad Med J. 72 (852): 594–8. doi:10.1136/pgmj.72.852.594. PMC . PMID 8977940.
- Holmes PW, Barter CE, Pierce RJ (September 1992). "Chronic persistent cough: use of ipratropium bromide in undiagnosed cases following upper respiratory tract infection". Respir Med. 86 (5): 425–9. doi:10.1016/S0954-6111(06)80010-7. PMID 1462022.
- International Society for the Study of Cough
- Theobromine inhibits sensory nerve activation and cough
- Usmani, Omar S.; Belvisi, Maria G.; Patel, Hema J.; Crispino, Natascia; Birrell Mark A.; Korbonits, Márta; Korbonits, Dezső; Barnes, Peter J. (November 17, 2004). "Theobromine inhibits sensory nerve activation and cough". FASEB Journal. 19 (2): 231–3. doi:10.1096/fj.04-1990fje. PMID 15548587. Retrieved 2008-07-04.
The present study demonstrates that theobromine, a methylxanthine derivative present in cocoa, effectively inhibits citric acid-induced cough in guinea-pigs in vivo. Furthermore, in a randomized, double-blind, placebo controlled study in man, theobromine suppresses capsaicin-induced cough with no adverse effects. We also demonstrate that theobromine directly inhibits capsaicin-induced sensory nerve depolarization of guinea-pig and human vagus nerve suggestive of an inhibitory effect on afferent nerve activation.
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