3D model (Jmol)
|E number||E332 (antioxidants, ...)|
|Molar mass||306.395 g/mol|
|Melting point||180 °C (356 °F; 453 K)|
|Boiling point||230 °C (446 °F; 503 K)|
|Solubility||soluble in glycerin
insoluble in ethanol (95%)
|Lethal dose or concentration (LD, LC):|
LD50 (median dose)
|170 mg/kg (IV, dog)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid with the molecular formula K3C6H5O7. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. It contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent.
Potassium citrate is rapidly absorbed when given by mouth and is excreted in the urine. Since it is an alkaline salt it is effective in reducing the pain and frequency of urination when these are caused by highly acidic urine. It is used for this purpose in dogs and cats, but is chiefly employed as a non-irritating diuretic.
It is widely used to treat urinary calculi (kidney stones) and is often used by patients with cystinuria.[medical citation needed] A study of 500 patients with recurrent stones found that it reduced the frequency of stones from 2 per year to a half per year.
A brand, Cytra-K Oral Solution, diluted with a glassful of water, taken four times a day will usually maintain a urinary pH of 7.0-7.6 throughout most of the 24 hours without unpleasant side effects.
Potassium citrate is usually administered by mouth in dilute aqueous solution. This is because of its somewhat caustic effect on the stomach lining, and the potential for other mild health hazards.
In the United-States, in states where non-prescription potassium citrate is legal, the maximum allowable over-the-counter (OTC) dose for elemental potassium is regulated by the FDA to be no more than 100 mg (approximately 3% of the daily allowance). Pure potassium citrate contains 38.28% potassium.
- Tanner, G.A. "Potassium citrate improves renal function in rats with polycystic kidney disease". Journal of the American Society of Nephrology. Retrieved December 17, 2016.