Prednylidene

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Prednylidene
Prednylidene.png
Clinical data
ATC code
Identifiers
Synonyms (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylidene-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-one
CAS Number
PubChem CID
ChemSpider
UNII
ECHA InfoCard 100.009.060
Chemical and physical data
Formula C22H28O5
Molar mass 372.455
3D model (Jmol)
 NYesY (what is this?)  (verify)

Prednylidene is a glucocorticoid[1] for systemic use.

Substitution at position 16 also leads to more potent corticosteroids. The additional steric bulk introduced by such substituents adjacent to the dihydroxyacetone side chain also protects that moiety against metabolic degradation.

References[edit]