Primary cutaneous amyloidosis

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Primary cutaneous amyloidosis
Macular amyloidosis.jpg
Macular amyloidosis, located on the right lumbar region of the back

Primary cutaneous amyloidosis is a form of amyloidosis associated with oncostatin M receptor.[1][2] This type of amyloidosis has been divided into the following types:[3]:520

  • Macular amyloidosis is a cutaneous condition characterized by itchy, brown, rippled macules usually located on the interscapular region of the back.[3]:521 Combined cases of lichen and macular amyloidosis are termed biphasic amyloidosis, and provide support to the theory that these two variants of amyloidosis exist on the same disease spectrum.[4]
  • Lichen amyloidosis is a cutaneous condition characterized by the appearance of occasionally itchy lichenoid papules, typically appearing bilaterally on the shins.[3]:521
  • Nodular amyloidosis is a rare cutaneous condition characterized by nodules that involve the acral areas.[3]:521

See also[edit]


  1. ^ "Amyloid".
  2. ^ Arita K, South AP, Hans-Filho G, et al. (January 2008). "Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis". Am. J. Hum. Genet. 82 (1): 73–80. doi:10.1016/j.ajhg.2007.09.002. PMC 2253984. PMID 18179886.
  3. ^ a b c d James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  4. ^ Lichen amyloidosis of the auricular concha Craig, E. (2006) Dermatology Online Journal 12 (5): 1, University of California, Davis Department of Dermatology

External links[edit]