Progressive outer retinal necrosis

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Progressive outer retinal necrosis
Other namesVaricella zoster virus retinitis (VZVR),[1]
Three Internal chambers of the Eye.png
Retina indicated at right

Progressive outer retinal necrosis, is an aggressive, necrotizing inflammation of the eye's retina caused by herpes varicella zoster virus. It is typically found in people with advanced AIDS, but has also been reported in those who are severely immunocompromised due to chemotherapy.[2]

The majority of those with progressive outer retinal necrosis develop severe vision loss and blindness.[3] Systemic antiviral drugs may improve the long-term visual outcome in those with the disease.[1]

See also[edit]


  1. ^ a b Moorthy RS, Weinberg DV, Teich SA, Berger BB, Minturn JT, Kumar S, Rao NA, Fowell SM, Loose IA, Jampol LM. "Management of varicella zoster virus retinitis in AIDS." Br J Ophthalmol. 1997 Mar;81(3):189–94. PMID 9135381
  2. ^ Copeland R, Phillpotts B. "Ocular Manifestations of HIV." January 20, 2005.
  3. ^ Holland GN. "The progressive outer retinal necrosis syndrome." Int Ophthalmol. 1994;18(3):163–5. PMID 7852023.