Prokarin (also known as Procarin) is a patented alternative medicine that consists of a mixture of histamine and caffeine. It is marketed as a treatment for multiple sclerosis, but there is no good medical evidence of its safety or effectiveness. The drug lacks any plausible basis in science and is very expensive.
- Tejani AM, Wasdell M, Spiwak R, Rowell G, Nathwani S (2012). "Carnitine for fatigue in multiple sclerosis". Cochrane Database Syst Rev (Systematic review). 5: CD007280. doi:10.1002/14651858.CD007280.pub3. PMID 22592719.
- Barrett S (15 May 2012). "Be Wary of Multiple Sclerosis "Cures"". Quackwatch. Retrieved November 2015. Check date values in:
- "The Prokarin Controversy", 2002–06, Laurie Long, MSA of King County
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