Prokineticin receptor

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prokineticin receptor 1
Identifiers
SymbolPROKR1
Alt. symbolsGPR73
Entrez10887
HUGO4524
OMIM607122
RefSeqNM_138964
UniProtQ8TCW9
Other data
LocusChr. 2 p14
prokineticin receptor 2
Identifiers
SymbolPROKR2
Alt. symbolsGPR73L1
Entrez128674
HUGO15836
OMIM607123
RefSeqNM_144773
UniProtQ8NFJ6
Other data
LocusChr. 20 p12.3

The prokineticin receptor is a G protein-coupled receptor which binds the peptide hormone prokineticin. There are two variants each encoded by a different gene (PROKR1, PROKR2).[1] These receptors mediate gastrointestinal smooth muscle contraction and angiogenesis.

References[edit]

  1. ^ Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY (2002). "Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor". J. Biol. Chem. 277 (22): 19276–80. doi:10.1074/jbc.M202139200. PMID 11886876.

External links[edit]