Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor for prokineticins. The encoded protein is similar in sequence to GPR73, another G protein-coupled receptor for prokineticins.
Deloukas P, Matthews LH, Ashurst J et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20.". Nature414 (6866): 865–71. doi:10.1038/414865a. PMID11780052.
Lin DC, Bullock CM, Ehlert FJ et al. (2002). "Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor.". J. Biol. Chem.277 (22): 19276–80. doi:10.1074/jbc.M202139200. PMID11886876.
Battersby S, Critchley HO, Morgan K et al. (2004). "Expression and regulation of the prokineticins (endocrine gland-derived vascular endothelial growth factor and Bv8) and their receptors in the human endometrium across the menstrual cycle". J. Clin. Endocrinol. Metab.89 (5): 2463–9. doi:10.1210/jc.2003-032012. PMID15126578.
Pasquali D, Rossi V, Staibano S et al. (2006). "The endocrine-gland-derived vascular endothelial growth factor (EG-VEGF)/prokineticin 1 and 2 and receptor expression in human prostate: Up-regulation of EG-VEGF/prokineticin 1 with malignancy". Endocrinology147 (9): 4245–51. doi:10.1210/en.2006-0614. PMID16763065.