Prokineticin receptor 2

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Prokineticin receptor 2
Symbols PROKR2 ; GPR73L1; GPR73b; GPRg2; HH3; KAL3; PKR2; dJ680N4.3
External IDs OMIM607123 MGI2181363 HomoloGene16368 IUPHAR: 336 ChEMBL: 5548 GeneCards: PROKR2 Gene
RNA expression pattern
PBB GE PROKR2 gnf1h10315 s at tn.png
More reference expression data
Species Human Mouse
Entrez 128674 246313
Ensembl ENSG00000101292 ENSMUSG00000050558
UniProt Q8NFJ6 Q8K458
RefSeq (mRNA) NM_144773 NM_144944
RefSeq (protein) NP_658986 NP_659193
Location (UCSC) Chr 20:
5.3 – 5.31 Mb
Chr 2:
132.34 – 132.39 Mb
PubMed search [1] [2]

Prokineticin receptor 2 (PKR2), is a G protein-coupled receptor encoded by the PROKR2 gene in humans.[1]

Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor for prokineticins. The encoded protein is similar in sequence to GPR73, another G protein-coupled receptor for prokineticins.[1]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.