|AHFS/Drugs.com||Micromedex Detailed Consumer Information|
|Elimination half-life||20-40 hr|
|CompTox Dashboard (EPA)|
|Chemical and physical data|
|Molar mass||284.42 g·mol−1|
|3D model (JSmol)|
Promazine (brand name Sparine) is a medication that belongs to the phenothiazine class of antipsychotics. An older medication used to treat schizophrenia, it is still prescribed, alongside newer agents such as olanzapine and quetiapine. It has predominantly anticholinergic side effects, though extrapyramidal side effects are not uncommon either. It readily dissolves in alcohol.
Promazine has been approved for human use in the United States, although it has been discontinued. It is available in the US for veterinary use under the names Promazine and Tranquazine where it is primarily administered to horses, by intravenous or intramuscular injection, as a preanesthetic agent. It is generally understood to induce moderate sedation. It is also an antiemetic, antispasmodic and hypothermic agent.
Additionally it is used to lower blood pressure in animals suffering from laminitis and renal failure. 
(TCAs and TeCAs)