Promazine (brand name Sparine) is a medication that belongs to the phenothiazine class of antipsychotics. An older medication used to treat schizophrenia, it is still prescribed, alongside newer agents such as olanzapine and quetiapine. It has predominantly anticholinergic side effects, though extrapyramidal side effects are not uncommon either.
Promazine has been approved for human use in the United States, although it has been discontinued. It is available in the US for veterinary use under the names Promazine and Tranquazine.